The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Jun. 27, 2019
Applicant:
Apotex Inc., Toronto, CA;
Inventors:
Fabio E. S. Souza, Mississauga, CA;
Bahareh Khalili, Mississauga, CA;
Assignee:
Apotex Inc., Toronto, Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); A61K 31/519 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 9/20 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention provides a novel crystalline form of Ribociclib succinate, Ribociclib succinate Form APO-I, including Ribociclib succinate, benzyl alcohol and water, compositions thereof, processes for the preparation thereof, and the use of this crystalline form in the treatment of conditions associated with increased CDK4/6 kinase activity, and in particular, cancers, including certain forms of breast cancer.