The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2020

Filed:

Apr. 25, 2018
Applicant:

3m Innovative Properties Company, St. Paul, MN (US);

Inventors:

Stephen B. Roscoe, Woodbury, MN (US);

Myungchan Kang, Woodbury, MN (US);

Evan D. Brutinel, Inver Grove Heights, MN (US);

Jesse D. Miller, Ann Arbor, MI (US);

Renee K. Cline, Blaine, MN (US);

Minghua Dai, Plymouth, MN (US);

Hsi-Chou Liu, Woodbury, MN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 33/53 (2006.01); G01N 33/558 (2006.01);
U.S. Cl.
CPC ...
B01L 3/5029 (2013.01); B01L 3/502 (2013.01); G01N 33/5304 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0825 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0478 (2013.01); G01N 33/558 (2013.01);
Abstract

Assay devices are provided including a receptacle having a sample entry port; a plunger disposed within the receptacle; at least one reagent; a membrane attached to a first surface of the plunger; a wick providing capillary force; and a detection zone. The membrane includes a target conjugate zone in which affinity components are disposed. Capture compounds are immobilized in a detection zone, which is located between the target conjugate zone and the wick. A method of detecting a target analyte is also provided, including providing the assay device; providing a sample suspected to contain a target analyte; adding the sample onto the device; allowing the sample to travel along the membrane until the sample reaches the detection zone; immobilizing the target analyte through reaction of the target analyte with the capture compounds; reacting the immobilized target analyte with a reagent to generate a detectable signal; and detecting the generated signal.


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