The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2020

Filed:

Aug. 01, 2014
Applicants:

Hans F. Schmitthenner, Rush, NY (US);

Stephanie Beach, Douglassville, PA (US);

Taylor Barrett, Middletown, PA (US);

Chelsea Weidman, Rochester, NY (US);

Inventors:

Hans F. Schmitthenner, Rush, NY (US);

Stephanie Beach, Douglassville, PA (US);

Taylor Barrett, Middletown, PA (US);

Chelsea Weidman, Rochester, NY (US);

Assignee:

Rochester Institute of Technology, Rochester, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/14 (2006.01); A61K 49/10 (2006.01); A61K 49/00 (2006.01); C07F 1/08 (2006.01); C07F 5/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/14 (2013.01); A61K 49/0032 (2013.01); A61K 49/0056 (2013.01); A61K 49/108 (2013.01); C07F 1/08 (2013.01); C07F 5/00 (2013.01);
Abstract

Targeted molecular imaging agents (TMIAs) are derived from coupling together pre-formed amino acids with imaging agents attached to their side chains. These peptide-based imaging agents may synthesized from a single or multiple preformed amino acids containing multi-modal, multi-chelated metal, multi-dye imaging agents, or combinations of these, on the side chains of resultant peptides. These imaging amino acids or peptides may be conjugated directly, or activated, or attached to linkers to which targeting groups, such as peptides, proteins, antibodies, aptamers, or small molecule inhibitors, may be conjugated in the final steps of the synthesis to form a wide variety of TMIAs.


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