The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Dec. 22, 2016
Applicant:
X4 Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Robert D. Arbeit, West Newton, MA (US);
Paula Marie Ragan, Belmont, MA (US);
Assignee:
X4 PHARMACEUTICALS, INC., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); A61K 9/48 (2006.01); C07D 235/14 (2006.01); A61K 9/00 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); A61P 37/04 (2006.01); A61P 17/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61K 9/0053 (2013.01); A61K 9/485 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01); A61P 17/12 (2018.01); A61P 37/04 (2018.01); C07D 235/14 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01);
Abstract
The present invention relates to methods of treating patients with WHIM syndrome or related disorders, such as myelokathexis, in which X4P-001 is administered in order to reduce the activity of CXCR4. The methods demonstrate surprising effectiveness, with comparatively little toxicity.