The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 07, 2020

Filed:

Sep. 15, 2014
Applicant:

Dow Global Technologies Llc, Midland, MI (US);

Inventors:

Meinolf Brackhagen, Walsrode, DE;

Matthias Knarr, Weser, DE;

Roland Adden, Walsrode, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/48 (2006.01); A61K 9/10 (2006.01); A61K 47/38 (2006.01); A61K 47/10 (2017.01); A61K 9/08 (2006.01); C08L 1/28 (2006.01);
U.S. Cl.
CPC ...
A61K 9/4866 (2013.01); A61K 9/08 (2013.01); A61K 9/10 (2013.01); A61K 9/4808 (2013.01); A61K 9/4816 (2013.01); A61K 9/4891 (2013.01); A61K 47/10 (2013.01); A61K 47/38 (2013.01); C08L 1/284 (2013.01);
Abstract

A liquid composition which comprises an organic liquid diluent and a hydroxyalkyl methylcellulose which has a certain distribution of substituted hydroxyalkoxyl groups and unsubstituted hydroxyalkoxyl groups is stable over an extended time period. In the hydroxyalkyl methylcellulose hydroxyalkoxyl groups are classified into a fraction (A) and a fraction (B), wherein fraction (A) represents the sum of all molar fractions of substituted hydroxyalkoxyl groups having hydroxyl groups substituted further with methoxyl groups and fraction (B) represents the sum of all molar fractions of unsubstituted hydroxyalkoxyl groups having hydroxyl groups not substituted further with methoxyl groups and wherein the ratio fraction (A)/fraction (B) is at least 0.30. The liquid composition is useful for preparing a solid dispersion comprising at least one active ingredient in at least one hydroxypropyl methylcellulose by spray-drying.


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