The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2020
Filed:
May. 10, 2018
Applicant:
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Jerry W. Shay, Dallas, TX (US);
Tsung-Po Lai, Dallas, TX (US);
Assignee:
The Board of Regents of the University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/683 (2018.01); C12Q 1/6855 (2018.01); C12Q 1/6858 (2018.01); C12Q 1/686 (2018.01); C12Q 1/6851 (2018.01); C12Q 1/6886 (2018.01); G16B 30/00 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/683 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6851 (2013.01); C12Q 1/6855 (2013.01); C12Q 1/6858 (2013.01); C12Q 1/6886 (2013.01); G16B 30/00 (2019.02);
Abstract
The present disclosure encompasses methods and compositions for analyzing telomeres of genomic DNA, including the length of one or more telomeres. In specific embodiments, methods and compositions are employed for identification of the length of the shortest telomere in a collection of genomic DNA. In particular cases, the method greatly suppresses amplification of intra-genomic DNA fragments in comparison to telomeres by hindering their amplification using particular adaptors.