The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2020
Filed:
Aug. 05, 2016
Applicant:
Academia Sinica, Taipei, TW;
Inventors:
Steve Roffler, Taipei, TW;
Huai-Yao Chuang, Taoyuan, TW;
Assignee:
Academia Sinica, Taipei, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/24 (2006.01); C12Q 1/40 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2402 (2013.01); C12N 9/24 (2013.01); C12Q 1/40 (2013.01); C12Y 302/01031 (2013.01); C12Y 302/01076 (2013.01); A61K 38/00 (2013.01);
Abstract
An engineered enzyme, comprising an amino acid sequence that is at least 80% identical to the amino acid sequence of a human beta-glucuronidase, wherein the engineered enzyme exhibits a higher level of alpha-iduronidase enzymatic activity as compared to the human beta-glucuronidase.