The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2020
Filed:
Jun. 19, 2013
Applicant:
Cambridge Enterprise Limited, Cambridge, GB;
Inventors:
Roger Pedersen, Cambridge, GB;
Willem Ouwehand, Cambridge, GB;
Thomas Moreau, Cambridge, GB;
Cedric Ghevaert, Cambridge, GB;
Matthew Trotter, Seville, ES;
Assignee:
Cambridge Enterprise Limited, Cambridge, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/19 (2015.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0644 (2013.01); C12N 2501/60 (2013.01); C12N 2506/03 (2013.01);
Abstract
This invention relates to the forward programming of pluripotent stem cells (PSCs) into megakaryocyte (MK) progenitor cells using the transcription factors GATA1, FLI1 and TAL1. Methods of producing megakaryocyte (MK) progenitor cells and subsequently differentiating them into mature megakaryocytes are provided.