The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2020
Filed:
Apr. 06, 2017
Applicant:
Kymab Limited, Cambridge, GB;
Inventors:
Jamie Campbell, Cambridge, GB;
Nikole Sandy Nee Waddell, Cambridge, GB;
Stephen D. Gillies, Carlisle, MA (US);
Volker Germaschewski, Cambridge, GB;
Cassandra van Krinks, Cambridge, GB;
Ian Kirby, Cambridge, GB;
Miha Kosmac, Cambridge, GB;
Steve Arkinstall, Cambridge, GB;
Thomas Gallagher, Cambridge, GB;
Assignee:
Kymab Limited, , GB;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 14/55 (2006.01); C07K 16/46 (2006.01); C07K 19/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); C07K 14/55 (2013.01); C07K 16/28 (2013.01); C07K 16/2803 (2013.01); C07K 16/468 (2013.01); C07K 19/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/524 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/71 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01); C07K 2319/74 (2013.01);
Abstract
The present invention relates to anti-PD-L1 antibodies, bispecific antibodies containing one domain with specificity to PD-L1, and to immunocytokines comprising an anti-PD-L1 antibody fused to a cytokine, such as IL-2. The present invention also provides methods of treatment, uses and pharmaceutical compositions comprising the antibodies, bispecific antibodies and immunocytokines.