The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2020
Filed:
May. 03, 2019
Novo Nordisk A/s, Bagsvaerd, DK;
Wouter Frederik Johan Hogendorf, Valby, DK;
Henning Thoegersen, Farum, DK;
Nicholas Raymond Cox, Seattle, WA (US);
Patrick J. Knerr, Plainfield, IN (US);
Richard DiMarchi, Carmel, IN (US);
Brian Finan, Indianapolis, IN (US);
Jesper F. Lau, Farum, DK;
Steffen Reedtz-Runge, Bikeroed, DK;
Fa Liu, Sammamish, WA (US);
Novo Nordisk A/S, Bagsvaerd, DK;
Abstract
The present invention relates to novel peptides that are derivatives of glucose-dependent insulinotropic polypeptide (GIP) analogues having improved physical stability in solution and a protracted profile of action. More particularly the invention relates to such peptides that are agonists at the GIP receptor and to their use in weight management or for treatment of diseases such as obesity, diabetes or non-alcoholic steatohepatitis (NASH). The peptides comprise a lysine residue at a position corresponding to position 24 of hGIP(1-31), and comprise a negatively charged modifying group attached to the epsilon amino group of the lysine residue.