The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2020
Filed:
Oct. 28, 2016
Applicant:
Intercept Pharmaceutical, Inc., New York, NY (US);
Inventor:
Gabriel M Galvin, San Diego, CA (US);
Assignee:
INTERCEPT PHARMACEUTICALS, INC., New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 9/00 (2006.01); C07J 17/00 (2006.01); C07J 31/00 (2006.01); C07J 41/00 (2006.01); C07J 43/00 (2006.01);
U.S. Cl.
CPC ...
C07J 9/005 (2013.01); C07J 9/00 (2013.01); C07J 17/00 (2013.01); C07J 31/006 (2013.01); C07J 41/0061 (2013.01); C07J 43/003 (2013.01);
Abstract
The present application relates to a method of preparing a bile acid derivative or a pharmaceutical acceptable salt, solvate, or amino acid conjugate thereof, comprising direct alkylation of a carbon atom at the C-6 position of 7 keto lithocholic acid (KLCA) with an alkylating agent and reduction of a keto group at the C-7 position.