The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2020
Filed:
Jan. 11, 2017
Applicant:
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Inventors:
Gary Glick, Ann Arbor, MI (US);
Shomir Ghosh, Brookline, MA (US);
Edward James Olhava, Newton, MA (US);
William R. Roush, Jupiter, FL (US);
Roger Jones, Martinsville, NJ (US);
Assignee:
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C07H 21/02 (2006.01); A61K 31/7084 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07H 21/00 (2013.01); A61K 31/7084 (2013.01); A61K 39/3955 (2013.01); C07H 21/02 (2013.01); C07K 16/2818 (2013.01); A61K 2039/505 (2013.01);
Abstract
This disclosure features dinucleotide compounds that modulate Stimulator of Interferon Genes (STING) activity, for use for example in the treatment of cancer. This disclosure also features compositions as well as other methods of using and making the same (Formula (A)). A and B are each independently selected from the group consisting of Formulae (i), (ii), (iii), and (iv).