The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2020

Filed:

Jul. 21, 2017
Applicant:

Crystal Pharmaceutical (Suzhou) Co., Ltd., Suzhou, Jiangsu, CN;

Inventors:

Minhua Chen, Suzhou, CN;

Yanfeng Zhang, Suzhou, CN;

Yuhao Chen, Suzhou, CN;

Hui Gao, Suzhou, CN;

Fei Lu, Suzhou, CN;

Xiaoyu Zhang, Suzhou, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61P 35/00 (2006.01); A61K 31/4162 (2006.01); A61K 31/4709 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4162 (2013.01); A61K 31/4709 (2013.01); A61P 35/00 (2018.01); C07B 2200/13 (2013.01);
Abstract

The present disclosure relates to a novel crystalline form of Galunisertib, processes for preparation and use thereof. The present disclosure also relates to a pharmaceutical composition comprises the novel crystalline form of Galunisertib and use of the novel crystalline form of Galunisertib and pharmaceutical composition for preparing drugs treating disease. The crystalline form of the present disclosure has good stability, solubility and hygroscopicity, which has significant value for future drug optimization and development.


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