The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2020

Filed:

Oct. 01, 2018
Applicant:

Meiji Seika Pharma Co., Ltd., Chuo-ku, Tokyo, JP;

Inventors:

Takao Abe, Kanagawa, JP;

Takeshi Furuuchi, Kanagawa, JP;

Yoshiaki Sakamaki, Kanagawa, JP;

Nakako Mitsuhashi, Kanagawa, JP;

Yumiko Saito, Kanagawa, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/439 (2006.01); C07D 471/08 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/08 (2013.01); A61K 31/439 (2013.01); A61K 45/06 (2013.01); C07B 2200/13 (2013.01);
Abstract

A process for producing a compound of the following Formula (VII-CR): The process involving providing a compound represented by the following Formula (VI): in a case where the RONHC(═O) side chain in the compound of the Formula (VI) has a protecting group, removing the protecting group from the compound of the Formula (VI) with an acid, and adding an ester-based poor solvent to the resultant reaction solution to precipitate the compound of Formula (VII-CR), wherein in the compounds of the Formulas (VII-CR) and (VI), Ris a Calkyl or a heterocycle.


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