The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2020
Filed:
Jun. 09, 2017
Applicant:
Crystal Pharmaceutical (Suzhou) Co., Ltd., Suzhou, Jiangsu, CN;
Inventors:
Assignee:
Crystal Pharmaceuticals (Suzhou) Co., Ltd., Suzhou, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 35/00 (2006.01); A61K 31/444 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/444 (2013.01); A61P 35/00 (2018.01); C07B 2200/13 (2013.01);
Abstract
The present disclosure relates to novel crystalline forms of PLX3397 hydrochloride and processes for preparation thereof. The crystalline forms of PLX3397 hydrochloride provided by the present disclosure have higher solubility, larger particle size which is favorable for separation in the subsequent production process, and good stability, especially mechanical stability. These novel crystalline forms of PLX3397 hydrochloride provide a better choice for PLX3397 drug products and are of great value for drug development.