The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 31, 2020
Filed:
Sep. 02, 2016
Applicant:
Mallinckrodt Llc, Hazelwood, MO (US);
Inventors:
Bobby N. Trawick, Florissant, MO (US);
David W. Berberich, St. Peters, MO (US);
Christopher W. Grote, Webster Groves, MO (US);
Assignee:
Mallinckrodt LLC, Hazelwood, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/167 (2006.01); A61K 31/472 (2006.01); A61K 31/485 (2006.01); C07D 217/20 (2006.01); C07D 221/28 (2006.01); C07D 489/00 (2006.01); C07D 489/02 (2006.01); C07D 489/10 (2006.01); C07D 489/08 (2006.01);
U.S. Cl.
CPC ...
C07D 217/20 (2013.01); A61K 31/167 (2013.01); A61K 31/472 (2013.01); A61K 31/485 (2013.01); C07D 221/28 (2013.01); C07D 489/00 (2013.01); C07D 489/02 (2013.01); C07D 489/08 (2013.01); C07D 489/10 (2013.01);
Abstract
The present invention provides (+)-morphinans comprising Toll-like receptor 9 (TLR9) antagonist activity, as well as methods for using the (+)-morphinans to treat pain. Also provided are pharmaceutical combination compositions comprising a (+)-morphinan and an opioid agonist/monoamine reuptake inhibitor, as well as methods for using the combination compositions to treat pain.