The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 2020

Filed:

Mar. 14, 2014
Applicants:

Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Barbara B. Kahn, Cambridge, MA (US);

Mark A. Herman, Needham, MA (US);

Alan Saghatelian, La Jolla, CA (US);

Edwin Homan, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 69/22 (2006.01); G01N 33/92 (2006.01); C07D 495/04 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
C07C 69/22 (2013.01); C07D 495/04 (2013.01); G01N 33/5308 (2013.01); G01N 33/92 (2013.01); G01N 2800/02 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including diabetes-related disorders, Metabolic Syndrome, polycystic ovarian syndrome, cancer, and inflammatory disorders—using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects.


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