The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2020

Filed:

Dec. 14, 2018
Applicant:

Thermo Finnigan Llc, San Jose, CA (US);

Inventors:

Jason S. Cole, Austin, TX (US);

Edward B. McCauley, Cedar Park, TX (US);

Assignee:

THERMOS FINNIGAN LLC, San Jose, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
H01J 49/00 (2006.01); G01N 33/00 (2006.01); H01J 49/16 (2006.01); H01J 49/26 (2006.01);
U.S. Cl.
CPC ...
H01J 49/0027 (2013.01); G01N 33/0006 (2013.01); H01J 49/0009 (2013.01); H01J 49/168 (2013.01); H01J 49/26 (2013.01);
Abstract

A calibration device and a method of calibrating a mass spectrometer are described where two or more immiscible mass spectrometry calibration compounds in close proximity to each other share a common headspace volume above their liquid surfaces. This arrangement allows each calibrant to evaporate at differing rates while allowing the headspace concentrations to remain relatively unchanged over time (forming a quasi-equilibrium calibrant mixture). The mixture is either delivered to an ion source of a mass spectrometer or to a vacuum pump via a flow restrictor from a calibration vial. The calibrant gas mixture in the headspace volume may be used to calibrate a mass spectrometer.


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