The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2020

Filed:

Apr. 08, 2016
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Richard M. Crooks, College Station, TX (US);

Ian Richards, Austin, TX (US);

Josephine Hofstetter, Austin, TX (US);

Molly Kogan, Austin, TX (US);

Yi-Ju Tsai, Austin, TX (US);

Long Luo, Austin, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); G01N 33/543 (2006.01); G01N 33/48 (2006.01); G01N 27/447 (2006.01); G01N 27/26 (2006.01); G01N 27/416 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
G01N 27/3278 (2013.01); G01N 27/26 (2013.01); G01N 27/4161 (2013.01); G01N 27/447 (2013.01); G01N 33/48 (2013.01); G01N 33/5438 (2013.01); G01N 33/54306 (2013.01); G01N 33/54313 (2013.01); G01N 33/74 (2013.01); G01N 2333/58 (2013.01);
Abstract

Provided herein are methods and devices for the detection of analytes. The methods employ particles formed from a first metal conjugated to analytes. The analyte conjugated to the particle formed from the first metal can be accumulated at a working electrode. The first metal can be galvanically exchanged with ions of a second metal to form a layer of the first metal at the working electrode. The first metal can then be electrochemically detected and/or quantified. Using this method, analytes can be detected at low concentrations a few femtomolar via anodic stripping voltammetry, with no washing steps or electrode modifications.


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