The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2020
Filed:
Jan. 21, 2016
GE Healthcare Bio-sciences Corp., Marlborough, MA (US);
John Richard Nelson, Niskayuna, NY (US);
Qingyan Au, Irvine, CA (US);
Wei Gao, Niskayuna, NY (US);
Ryan Charles Heller, Niskayuna, NY (US);
Nicholas Hoe, Garden Grove, CA (US);
Nam Tran, Aliso Viejo, CA (US);
Nichole Lea Wood, Niskayuna, NY (US);
GE Healthcare Bio-Sciences Corp., Marlborough, MA (US);
Abstract
The invention discloses a method for determining a nucleotide sequence of a nucleic acid segment present in a biological sample, comprising the steps of: a) generating a fluorescent image of the sample by a protocol comprising immunofluorescence detection of at least five different target proteins in the sample; b) selecting a region of interest of the sample by comparing the image to a predetermined criterion; c) removing a subsample from the region of interest, and; d) determining a nucleotide sequence of a nucleic acid segment present in the subsample.