The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2020
Filed:
Feb. 23, 2016
Applicant:
Radiometer Medical Aps, Brønshøj, DK;
Inventors:
Assignee:
RADIOMETER MEDICAL APS, Brønshøj, DK;
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/78 (2006.01); C12Q 1/34 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); C07H 21/04 (2006.01); C12N 9/86 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/34 (2013.01); C12N 9/86 (2013.01); C12N 15/00 (2013.01);
Abstract
The invention relates to a mutant polypeptide havingactivity, where the polypeptide both retains thermostable activity in the presence of reagents that modify thiol groups. The invention further relates to methods for producing the mutant polypeptide; and to a sensor comprising the mutant polypeptide for use in the measurement of creatinine in samples of physiological fluids. Additionally, the invention teaches how to use the mutant polypeptide to enhance the life-time of a creatinine sensor, and a method for producing the sensor.