The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2020
Filed:
Dec. 23, 2014
Applicant:
Genomatica, Inc., San Diego, CA (US);
Inventors:
Anthony P. Burgard, Bellefonte, PA (US);
Robin E. Osterhout, San Diego, CA (US);
Stephen J. Van Dien, Encinitas, CA (US);
Priti Pharkya, San Diego, CA (US);
Tae Hoon Yang, San Diego, CA (US);
Jungik Choi, San Diego, CA (US);
Assignee:
Genomatica, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/18 (2006.01); C12P 7/42 (2006.01); C07K 14/245 (2006.01); C12N 9/00 (2006.01); C12N 1/20 (2006.01); C12N 9/88 (2006.01); C12N 9/52 (2006.01); C12N 15/52 (2006.01); C12N 9/16 (2006.01); C12N 9/02 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12P 7/18 (2013.01); C07K 14/245 (2013.01); C12N 1/20 (2013.01); C12N 9/0036 (2013.01); C12N 9/0057 (2013.01); C12N 9/1205 (2013.01); C12N 9/16 (2013.01); C12N 9/52 (2013.01); C12N 9/88 (2013.01); C12N 9/93 (2013.01); C12N 15/52 (2013.01); C12P 7/42 (2013.01); C12Y 106/01002 (2013.01); C12Y 110/03 (2013.01); C12Y 207/0104 (2013.01); C12Y 301/00 (2013.01); C12Y 301/02 (2013.01); C12Y 301/02002 (2013.01); C12Y 304/21092 (2013.01); C12Y 401/01031 (2013.01); C12Y 401/01032 (2013.01);
Abstract
The invention is directed to a non-naturally occurring microbial organism comprising a first attenuation of a succinyl-CoA synthetase or transferase and at least a second attenuation of a succinyl-CoA converting enzyme or a gene encoding a succinate producing enzyme within a multi-step pathway having a net conversion of succinyl-CoA to succinate.