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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10597639 B1

PDFFull Text
Date of Patent:
Mar. 24, 2020

Filed:

Oct. 20, 2017

3d-printed scaffold device for cell transplantation

Applicants:

Jeffrey Millman, St. Louis, MO (US);

Jiwon Song, St. Louis, MO (US);

Inventors:

Jeffrey Millman, St. Louis, MO (US);

Jiwon Song, St. Louis, MO (US);

Assignee:

Washington University, St. Louis, MO (US);

Attorney:

Polsinelli PC

Primary Examiner:

Bin Shen

Int. Cl.
CPC ...
C12N 5/071 (2010.01); A61F 2/02 (2006.01); A61K 35/39 (2015.01); A61K 45/06 (2006.01); A61L 27/38 (2006.01); C12N 5/0775 (2010.01); A61P 5/50 (2006.01); C08F 220/14 (2006.01); B33Y 80/00 (2015.01); C08F 220/28 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0677 (2013.01); A61F 2/02 (2013.01); A61K 35/39 (2013.01); A61K 45/06 (2013.01); A61L 27/3834 (2013.01); A61L 27/3895 (2013.01); A61P 5/50 (2018.01); B33Y 80/00 (2014.12); C08F 220/14 (2013.01); C08F 220/28 (2013.01); C12N 5/0662 (2013.01); C12N 5/0676 (2013.01); A61F 2/022 (2013.01); A61F 2240/001 (2013.01); C12N 2506/02 (2013.01); C12N 2506/1369 (2013.01); C12N 2506/1392 (2013.01); C12N 2506/22 (2013.01); C12N 2513/00 (2013.01); C12N 2533/30 (2013.01);
Abstract

Disclosed herein is a 3D-printed, biocompatible macroporous device that houses stem cell derived β-cell (SC-β cell) clusters within a degradable fibrin gel. Cluster sizes are used that avoid severe hypoxia within 3D-printed devices and a microwell-based technique is used for resizing clusters within this range. 3D-printed devices may function for at least 12 weeks, are retrievable, and maintain structural integrity.

Find Patent Forward Citations

Millman, Jeffrey. (2020). 3d-printed scaffold device for cell transplantation (U.S. Patent No. 10597639). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10597639

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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