The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2020
Filed:
Dec. 21, 2017
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 291/02 (2006.01); C07D 285/00 (2006.01); C07D 273/00 (2006.01); A61P 31/04 (2006.01); C07D 417/12 (2006.01); C07D 413/12 (2006.01); C07D 419/12 (2006.01);
U.S. Cl.
CPC ...
C07D 291/02 (2013.01); A61P 31/04 (2018.01); C07D 273/00 (2013.01); C07D 285/00 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 419/12 (2013.01);
Abstract
Compounds that regulate quorum sensing in Staphylococcal bacteria and in particular inare provided. Compounds are described in formulas I, II, III, IV, V and VI herein. One or more compounds herein can be employed to inhibit QS and to thus inhibit virulence inbacteria and in particular in. Compounds herein and pharmaceutical compositions containing one or more of these compounds are useful, for example, in treating infections ofbacteria and in particular of. Methods for treating such bacterial infections are provided.