The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2020

Filed:

Oct. 30, 2018
Applicant:

Advanced Accelerator Applications (Italy) Srl, Pozzilli, IT;

Inventors:

Francesco de Palo, Ivrea, IT;

Lorenza Fugazza, Ivrea, IT;

Donato Barbato, Ivrea, IT;

Maurizio Mariani, Ivrea, IT;

Daniela Chicco, Albiano d'Ivrea, IT;

Giovanni Tesoriere, Noicattaro, IT;

Clementina Brambati, Turin, IT;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 51/08 (2006.01); A61K 47/12 (2006.01); A61K 47/22 (2006.01); A61K 47/18 (2017.01); A61K 51/12 (2006.01);
U.S. Cl.
CPC ...
A61K 51/083 (2013.01); A61K 47/12 (2013.01); A61K 47/18 (2013.01); A61K 47/22 (2013.01); A61K 51/121 (2013.01); A61K 51/08 (2013.01);
Abstract

The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradation. The use of two stabilizers introduced during the manufacturing process at different stages was found to be of particular advantage.


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