The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2020
Filed:
Mar. 19, 2015
University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
University of New Orleans, New Orleans, LA (US);
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Baton Rough, LA (US);
Jay Kennedy Kolls, Pittsburgh, PA (US);
Mingquan Michael Zheng, Upper St. Clair, PA (US);
Yang Cai, New Orleans, LA (US);
Taylor John Eddens, Pittsburgh, PA (US);
David M. Ricks, Pittsburgh, PA (US);
University of Pittsburgh—Of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
University of New Orleans, New Orleans, LA (US);
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, Baton Rouge, LA (US);
Abstract
Pneumonia due to the fungusis a life-threatening infection that occurs in immunocompromised patients. The inability to culture the organism as well as the lack of a sequenced genome has hindered antigen discovery that could be useful in developing effective vaccines, therapeutic antibodies and diagnostic methods. A method of surface proteomics ofthat reliably detects surface proteins that are conserved inis described. In particular, eight identifiedsurface proteins are described. Methods of eliciting immune responses against the identified proteins, generating therapeutic antibodies against the identified proteins, as well as diagnostic methods based on the identified peptides are described.