The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 24, 2020

Filed:

Mar. 11, 2016
Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Atta Behfar, Rochester, MN (US);

Andre Terzic, Rochester, MN (US);

William Cook, Rochester, MN (US);

Ruben Crespo, Rochester, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 8/11 (2006.01); A61K 8/14 (2006.01); A61K 8/98 (2006.01); A61K 35/16 (2015.01); A61Q 19/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5089 (2013.01); A61K 8/11 (2013.01); A61K 8/14 (2013.01); A61K 8/983 (2013.01); A61K 9/5073 (2013.01); A61K 35/16 (2013.01); A61Q 19/00 (2013.01); A61K 2800/10 (2013.01); A61K 2800/412 (2013.01);
Abstract

A method of delivering exosomes and other micro vesicles to a biological target includes the steps of 1) providing blood, (2) separating plasma from the provided blood, and (3) separating the solution with the exosomes therefrom, (4) encapsulating the exosomes, and (5) delivering the exosomes. The step of encapsulation may be accomplished by water bead process, alginate bead process, spray drying bead formation, or plating. The biological target may be a human or animal heart, bone/joint, wound or skin. A method of encapsulating an exosome, a method of using an encapsulated exosome, compositions including encapsulated exosomes, and an encapsulated exosome per se are also disclosed.


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