The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2020
Filed:
Apr. 28, 2016
University of Washington, Seattle, WA (US);
Minoru Taya, Mercer Island, WA (US);
University of Washington, Seattle, WA (US);
Abstract
Nano-actuators having a helical member formed with a ferromagnetic shape memory alloy (FSMA) are disclosed that are elastically deformable between a compressed state and an expanded state by the application of a magnetic field. The nano-actuators may include a ferromagnetic head portion, that may be formed from the FSMA or from another material. A thin biocompatible external layer provides a platform for attaching a ligand that is selected to bind with a target cell type, for example, a target cancer cell. The nano-actuators are magnetically propelled to the target cells, and oscillated and/or rotated to mechanically damage the target cells to induce apoptosis. The nano-actuators may be formed by electro deposition of the FSMA into a nano-helical template.