The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2020

Filed:

Mar. 19, 2018
Applicant:

Tepha, Inc., Lexington, MA (US);

Inventors:

Amit Ganatra, Attleboro, MA (US);

Fabio Felix, Foxborough, MA (US);

Bhavin Shah, Lowell, MA (US);

Matthew Bernasconi, Norwood, MA (US);

Said Rizk, Windham, NH (US);

David P. Martin, Arlington, MA (US);

Simon F. Williams, Cambridge, MA (US);

Assignee:

Tepha, Inc., Lexington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); D01F 6/62 (2006.01); A61L 17/10 (2006.01); A61L 31/06 (2006.01); A61L 31/14 (2006.01); B29C 55/00 (2006.01); D01F 8/14 (2006.01); D01D 5/08 (2006.01); D02G 3/04 (2006.01); B29K 73/00 (2006.01); B29L 31/00 (2006.01); B29K 673/00 (2006.01);
U.S. Cl.
CPC ...
D01F 6/625 (2013.01); A61L 17/105 (2013.01); A61L 31/06 (2013.01); A61L 31/148 (2013.01); B29C 55/005 (2013.01); D01D 5/08 (2013.01); D01F 8/14 (2013.01); D02G 3/04 (2013.01); B29K 2073/00 (2013.01); B29K 2673/00 (2013.01); B29L 2031/731 (2013.01); D10B 2331/04 (2013.01); D10B 2331/041 (2013.01); D10B 2401/063 (2013.01); D10B 2509/04 (2013.01); D10B 2509/08 (2013.01);
Abstract

Resorbable multifilament yarns and monofilament fibers including poly-4-hydroxybutyrate and copolymers thereof with high tenacity or high tensile strength have been developed. The yarns and fibers are produced by cold drawing the multifilament yarns and monofilament fibers before hot drawing the yarns and fibers under tension at temperatures above the melt temperature of the polymer or copolymer. These yarns and fibers have prolonged strength retention in vivo making them suitable for soft tissue repairs where high strength and strength retention is required. The multifilament yarns have tenacities higher than 8.1 grams per denier, and in vivo, retain at least 65% of their initial strength at 2 weeks. The monofilament fibers retain at least 50% of their initial strength at 4 weeks in vivo. The monofilament fibers have tensile strengths higher than 500 MPa. These yarns and fibers may be used to make various medical devices for various applications.


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