The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2020
Filed:
Oct. 05, 2018
Applicant:
Ohio State Innovation Foundation, Columbus, OH (US);
Inventors:
Peixuan Guo, Dubin, OH (US);
Fengmei Pi, Columbus, OH (US);
Hui Li, San Francisco, CA (US);
Shaoying Wang, Middlesex, NJ (US);
Assignee:
Ohio State Innovation Foundation, Columbus, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 9/127 (2006.01); C12N 15/11 (2006.01); A61K 9/51 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/1273 (2013.01); A61K 9/51 (2013.01); A61K 9/513 (2013.01); A61P 35/00 (2018.01); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2310/51 (2013.01); C12N 2320/32 (2013.01);
Abstract
Disclosed herein are compositions comprising extracellular vesicles, such as exosomes, displaying an RNA nanoparticle on its surface. The RNA nanoparticle can target the extracellular vesicle to a given cell via a targeting moiety. The extracellular vesicle can also comprise a functional moiety, which can be used in treatment or diagnostics.