The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2020
Filed:
Oct. 14, 2015
Applicant:
Cellmid Limited, New South Wales, AU;
Inventors:
Maria Halasz, New South Wales, AU;
Darren Jones, New South Wales, AU;
Nico Mertens, Hertfordshire, GB;
Phillip Cunnah, Porto Salvo, PT;
Assignee:
CELLMID LIMITED, , AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61K 39/395 (2006.01); C07K 16/22 (2006.01); G01N 33/68 (2006.01); G01N 33/574 (2006.01); A61K 31/555 (2006.01); C07K 16/30 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 31/555 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); C07K 16/30 (2013.01); G01N 33/57407 (2013.01); G01N 33/57434 (2013.01); G01N 33/57488 (2013.01); G01N 33/6893 (2013.01); G01N 33/74 (2013.01); C07K 2317/24 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/626 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/475 (2013.01);
Abstract
The present disclosure is directed to isolated or recombinant proteins, such as antibodies, which bind to, and inhibit or reduce the function of, midkine (MK) and their use as therapeutic and/or diagnostic agents for midkine-related disorders. The present disclosure is also related to nucleic acid sequences which encode said proteins and their expression in recombinant host cells. In particular, the present disclosure is directed towards humanized antibodies derived from murine antibody IP14 which specifically bind to human MK.