The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2020

Filed:

Dec. 20, 2018
Applicant:

Medicago Inc., Quebec, CA;

Inventors:

Marc-Andre D'Aoust, Quebec, CA;

Pierre-Olivier Lavoie, Quebec, CA;

Manon Couture, St. Augustin de Desmaures, CA;

Lucie Poulin, Quebec, CA;

Louis-Philippe Vezina, Quebec, CA;

Assignee:

Medicago Inc., Quebec, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C07K 14/005 (2006.01); C07K 16/10 (2006.01); C12N 15/82 (2006.01); A61K 39/125 (2006.01); A61K 39/13 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/125 (2013.01); A61K 39/13 (2013.01); C07K 16/1009 (2013.01); C12N 7/00 (2013.01); C12N 15/8258 (2013.01); C07K 2317/10 (2013.01); C12N 2770/32322 (2013.01); C12N 2770/32323 (2013.01); C12N 2770/32351 (2013.01); C12N 2770/32623 (2013.01); C12N 2770/32634 (2013.01); C12N 2800/22 (2013.01);
Abstract

A method of producing a picornavirus-like particle (PVLP) in a plant is provided. The method comprises introducing a first nucleic acid and a second nucleic acid into the plant, portion of the plant, or a plant cell. The first nucleic acid comprising a first regulatory region active in the plant operatively linked to a nucleotide sequence encoding a polyprotein. The second nucleic acid comprises a second regulatory region active in the plant and operatively linked to a nucleotide sequence encoding one or more protease. The plant, portion of the plant, or plant cell is incubated under conditions that permit the expression of the nucleic acids, thereby producing the PVLP. A PVLP comprising the polyprotein is also provided.


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