The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2020
Filed:
Jun. 29, 2016
William Marsh Rice University, Houston, TX (US);
Kyriacos C. Nicolaou, Houston, TX (US);
Ruofan Li, Houston, TX (US);
Zhaoyong Lu, Houston, TX (US);
Te-ik Sohn, Andong, KR;
James Woods, Houston, TX (US);
Emmanouil N. Pitsinos, Houston, TX (US);
WILLIAM MARSH RICE UNIVERSITY, Houston, TX (US);
Abstract
In one aspect, the present disclosure provides shishijimicin analogs of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, antibody drug conjugates of the compounds are also provided.