The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2020

Filed:

Jun. 28, 2019
Applicant:

F.i.s.-fabbrica Italiana Sintetici S.p.a., Montecchio Maggiore (VI), IT;

Inventors:

Elena Brasola, Saccolongo, IT;

Filippo Tomasi, Brogliano, IT;

Loris Peruzzi, Lonigo, IT;

Assignee:

F.I.S.-FABBRICA ITALIANA SINTETICI S.P.A., Montecchio Maggiore (VI), IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); B01D 11/02 (2006.01); C07B 63/00 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); G01N 30/36 (2006.01); G01N 30/72 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); B01D 11/02 (2013.01); C07B 63/00 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); G01N 30/36 (2013.01); G01N 30/7233 (2013.01); G01N 2030/027 (2013.01);
Abstract

Object of the present invention are dimer impurities of the active ingredient Apixaban, analytical methods for identifying and/or quantifying them and a synthetic method for removing or limiting said impurities from Apixaban and synthetic precursors thereof.


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