The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2020
Filed:
Jan. 09, 2017
Pfizer Inc., New York, NY (US);
Thomas Allen Chappie, Carlisle, MA (US);
Jaclyn Louise Henderson, Cambridge, MA (US);
Joseph Michael Young, Castro Valley, CA (US);
Travis T. Wager, Brookline, MA (US);
Bethany Lyn Kormos, Somerville, MA (US);
Nandini Chaturbhai Patel, Waban, MA (US);
Simone Sciabola, Cambridge, MA (US);
Jamison Bryce Tuttle, Marblehead, MA (US);
Patrick Robert Verhoest, Newton, MA (US);
Joseph Walter Tucker, New London, CT (US);
Pfizer, Inc., New York, NY (US);
Abstract
The present invention provides compounds of Formula (I): and pharmaceutically acceptable salts thereof wherein the variables R, R, R, R, R, a and A are as defined herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D3-mediated (or D3-associated) disorders including, e.g., substance addiction, substance abuse, schizophrenia (e.g., its cognitive symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD or PD), Parkinson's disease, mania, anxiety, impulse control disorders, sexual disorders and depression.