The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2020

Filed:

Oct. 14, 2016
Applicant:

Thomas Jefferson University, Philadelphia, PA (US);

Inventor:

Paul F. Bray, Penn Valley, PA (US);

Assignee:

THOMAS JEFFERSON UNIVERSITY, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 9/10 (2006.01); C07D 209/12 (2006.01); C07D 209/14 (2006.01); C07D 401/04 (2006.01); A61K 31/437 (2006.01); A61K 31/444 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 9/10 (2018.01); C07D 209/12 (2013.01); C07D 209/14 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01);
Abstract

A substance of Formula (I) for use as a medicament for the treatment of cardiovascular diseases, wherein R is nitrogen or carbon; Ris selected from the group consisting of a hydrogen, a trifluoromethyl, a methyloxyphenyl, a phenyl, a C-Cphenylalkyl, a halogenated phenyl, a halogenated C-Cphenylalkyl, a trifluoromethyloxy, a trifluoromethyl oxyphenyl, and a C-Cpyridinylalkyl; Ris selected from the group consisting of a C-Calkyl alcohol optionally substituted with a C-Calkoxyphenyl, a C-CN-alkylmethanamine, a C-Calkoxymethyl, a C-Cphenylalkoxymethyl, a C-Ccyclopropylalkoxymethyl, and a methoxyethoxymethyl; and Ris a phenyl or a methoxypyridinyl; and Ris selected from the group consisting of a hydrogen, a cyano, a C-Csulfonyl, a nitro, and a trifluoromethyl.


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