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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10590105 B1

PDFFull Text
Date of Patent:
Mar. 17, 2020

Filed:

Jul. 05, 2017

1,3-dihydroxy-phenyl derivatives useful as immunomodulators

Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Kap-Sun Yeung, Madison, CT (US);

Katharine A. Grant-Young, Vieques, PR (US);

Juliang Zhu, North Haven, CT (US);

Mark G. Saulnier, Higganum, CT (US);

David B. Frennesson, Naugatuck, CT (US);

Zhaoxing Meng, Pennington, NJ (US);

Paul Michael Scola, Glastonbury, CT (US);

Assignee:

Bristol-Meyers Squibb Company, Princeton, NJ (US);

Attorney:

Sterne, Kessler, Goldstein & Fox P.L.L.C.

Primary Examiner:

Zinna Northington Davis

Int. Cl.
CPC ...
C07D 401/10 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 405/12 (2006.01); C07D 401/14 (2006.01); C07D 413/12 (2006.01); C07D 401/12 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01); A61K 31/498 (2006.01); A61K 45/06 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/10 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/498 (2013.01); A61K 45/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract

The present disclosure generally relates to compounds of formula (I), wherein R2 is a phenyl or pyridinyl moiety, useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.

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