The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2020
Filed:
Feb. 20, 2018
Applicant:
H. Lundbeck A/s, Valby, DK;
Inventors:
Mario Rottlander, Greve, DK;
Anette Graven Sams, Vaerlose, DK;
Xiaofang Wang, Shanghai, CN;
Debasis Das, Shanghai, CN;
Jian Hong, Shanghai, CN;
Shu Hui Chen, Calabasas, CA (US);
Assignee:
H. Lundbeck A/S, Valby, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 235/06 (2006.01); A61P 25/08 (2006.01); A61P 25/06 (2006.01); A61P 25/04 (2006.01); A61P 25/24 (2006.01); A61P 25/22 (2006.01); A61P 25/28 (2006.01); A61P 25/18 (2006.01); C07C 235/08 (2006.01); C07C 235/26 (2006.01);
U.S. Cl.
CPC ...
C07C 235/06 (2013.01); A61P 25/04 (2018.01); A61P 25/06 (2018.01); A61P 25/08 (2018.01); A61P 25/18 (2018.01); A61P 25/22 (2018.01); A61P 25/24 (2018.01); A61P 25/28 (2018.01); C07C 235/08 (2013.01); C07C 235/26 (2013.01); C07B 2200/07 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05);
Abstract
The present invention provides novel compounds which activate the Kv7 potassium channels. Exemplary compounds of the invention have the structure of Formula 1. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders responsive to the activation of Kv7 potassium channels.