The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2020
Filed:
Oct. 05, 2017
Applicant:
Bio-rad Laboratories, Inc., Hercules, CA (US);
Inventors:
Larry J. Cummings, Pleasant Hill, CA (US);
Jie He, South San Francisco, CA (US);
Assignee:
Bio-Rad Laboratories, Inc., Hercules, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C01B 25/32 (2006.01); B01D 15/20 (2006.01); B01J 20/04 (2006.01); B01J 20/34 (2006.01); C07K 1/18 (2006.01); C01B 25/455 (2006.01); B01J 20/282 (2006.01); C07K 1/20 (2006.01); C07K 1/22 (2006.01);
U.S. Cl.
CPC ...
C01B 25/327 (2013.01); B01D 15/203 (2013.01); B01J 20/048 (2013.01); B01J 20/282 (2013.01); B01J 20/3433 (2013.01); B01J 20/3475 (2013.01); C01B 25/455 (2013.01); C07K 1/18 (2013.01); C07K 1/20 (2013.01); C07K 1/22 (2013.01);
Abstract
Methods and compositions are provided for treatment of an apatite-based resin from which retained solutes have been eluted by an elution buffer that contains an alkali metal salt with solutions of calcium ion, phosphate ion, and hydroxide separately from any sample loading and elution buffers. The treatment solutions restore the resin, reversing the deterioration that is caused by the alkali metal salt in the elution buffer.