The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2020
Filed:
Sep. 02, 2016
Applicant:
Wayne State University, Detroit, MI (US);
Inventors:
Malathy Shekhar, Northville, MI (US);
Guangzhao Mao, Bloomfield Hills, MI (US);
Yanhua Zhang, Livonia, MI (US);
Assignee:
Wayne State University, Detroit, MI (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 31/53 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6923 (2017.08); A61K 31/53 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract
Pharmaceutical compositions, methods of treatment of proliferative diseases and commercial packages are provided according to aspects of the present invention which relate to a first therapeutic agent coupled to a nanoparticle, wherein the first therapeutic agent is SMI #8 or SMI #9 a pharmaceutically acceptable salt, ester, amide, stereoisomer, hydrate, or derivative of either thereof. According to particular aspects, the SMI #8 or SMI #9 is conjugated to gold nanoparticles.