The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 17, 2020

Filed:

Jul. 15, 2016
Applicants:

Emv Enhance (Hk) Limited, Central, HK;

Versitech Limited, Telegraph Bay, HK;

Inventors:

Fan Ngai Hung, Mid-Level, HK;

Jinxia Zhang, Tai Po, HK;

Kai Wang Kelvin To, Pokfulam, HK;

Johnson Yiu-Nam Lau, Houston, TX (US);

Kwok Yung Yuen, Pokfulam, HK;

Assignees:

EMV ENHANCE (HK) LIMITED, Hong Kong, HK;

VERSITECH LIMITED, Hong Kong, HK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4745 (2006.01); A61K 45/06 (2006.01); A61K 39/12 (2006.01); A61K 39/39 (2006.01); C07K 16/10 (2006.01); A61K 9/00 (2006.01); A61K 39/145 (2006.01); A61P 31/16 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A61K 9/0014 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/39 (2013.01); A61K 45/06 (2013.01); A61P 31/16 (2018.01); C07K 16/1018 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/575 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16234 (2013.01);
Abstract

Compositions and methods are described in which the topical application of a toll-like receptor 7 agonist or a toll-like receptor 9 agonist at or near a subdermal vaccination site provides an enhanced response to the vaccination. The enhanced response can be an elevated antibody titer relative to an untreated but vaccinated subject, and/or development of cross-species immunity to species not present in the vaccinating composition.


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