The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 17, 2020
Filed:
Jun. 24, 2014
Applicants:
Oyagen, Inc., Rochester, NY (US);
Harold C. Smith, Rochester, NY (US);
Ryan P. Bennett, Clifton Springs, NY (US);
Inventors:
Harold C. Smith, Rochester, NY (US);
Ryan P. Bennett, Clifton Springs, NY (US);
Assignee:
OyaGen, Inc., Rochester, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4745 (2006.01); G01N 33/68 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A61K 45/06 (2013.01); G01N 33/6845 (2013.01); G01N 2333/15 (2013.01); G01N 2333/163 (2013.01); G01N 2500/02 (2013.01); G01N 2500/10 (2013.01);
Abstract
The present invention relates to the use of camptothecin derivatives as anti-HIV agents that disrupt self-association of the viral infectivity factor (Vif) found in HIV and other retroviruses. The present invention also relates to methods of identifying agents that disrupt VIf self-association and methods of using these agents, including methods of treating or preventing HIV infection.