The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Jun. 13, 2018
Applicant:

Optrascan, Inc., Cupertino, CA (US);

Inventors:

Abhijeet Gholap, Cupertino, CA (US);

Anagha Jadhav, Cupertino, CA (US);

Gurunath Kamble, Cupertino, CA (US);

Assignee:

OPTRASCAN, INC., Cupertino, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2006.01); G06T 15/08 (2011.01); G06T 7/10 (2017.01); G01N 33/50 (2006.01); G06T 7/00 (2017.01); G06T 7/11 (2017.01); G01N 15/14 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
G06T 15/08 (2013.01); G01N 33/5091 (2013.01); G06K 9/00127 (2013.01); G06K 9/00147 (2013.01); G06T 7/0012 (2013.01); G06T 7/10 (2017.01); G06T 7/11 (2017.01); G01N 15/1475 (2013.01); G01N 2015/1006 (2013.01); G01N 2800/60 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/30004 (2013.01); G06T 2207/30024 (2013.01);
Abstract

In an automated method of determining potential efficacy of immunotherapy approaches, an automated slide scanning system with an image acquisition unit is provided. A sample slide with a mounted tissue sample is received by the automated slide scanning system. One or more slide images of the tissue sample are acquired with the image acquisition unit. At least one cell segmentation process is executed on the slide image in order to identify tissue cells. The cells are analyzed with at least one cell classification algorithm in order to identify a tumor cell percent positivity value and an immune cell percent positivity value, and a treatment efficacy score is subsequently calculated. Further features provided include pixel to pixel image registration, reconstruction, composite multi-layer viewing, and other image management tools.


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