The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Jan. 29, 2018
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventor:

Kieren A. Marr, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/569 (2006.01); C07K 16/14 (2006.01); G01N 33/66 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56961 (2013.01); C07K 16/14 (2013.01); G01N 33/54366 (2013.01); G01N 33/569 (2013.01); G01N 33/66 (2013.01); G01N 2400/02 (2013.01); G01N 2469/10 (2013.01);
Abstract

Disclosed herein are methods of detecting microbial infection in mammalian subjects comprising treatment of a sample and detection of galactofuranose (galF)-containing antigenic components utilizing monoclonal antibodies. The methods disclosed provide for pretreatment of biological samples, such as urine samples, to maximize detection of galF antigens and improvement of sensitivity of galF antigen detection assays. The methods include minimizing intelectin-1 binding to galF antigens and improvement of monoclonal antibody binding. The detection methods are useful for identifying the presence of microbial antigens related to bacterial, fungal, and parasitic pathogens, includingspecies,species,species,species,species, andspecies.


Find Patent Forward Citations

Marr, Kieren. (2020). Optimizing diagnostics for galactofuranose containing antigens (U.S. Patent No. 10585098). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10585098

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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