The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2020
Filed:
Jan. 13, 2014
Applicant:
Senex Biotechnology, Inc., Columbia, SC (US);
Inventors:
Igor B Roninson, Lexington, SC (US);
Donald C Porter, Columbia, SC (US);
Serena Altilia, Columbia, SC (US);
Assignee:
Senex Biotechnology, Inc., Columbia, SC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12Q 1/48 (2006.01); G01N 33/573 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/485 (2013.01); G01N 33/5008 (2013.01); G01N 33/573 (2013.01);
Abstract
The invention provides a method for determining the activity of an inhibitor of a target protein that has a deleterious effect on cell growth. The principle of the claimed method is that a compound that inhibits the function of an overexpressed protein will relieve the detrimental effect of such overexpression in a concentration-dependent manner, thereby allowing the determination of the activity of the compound in inhibiting its target protein in live cells.