The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Mar. 15, 2017
Applicant:

Conagen Inc., Bedford, MA (US);

Inventors:

Nicky C. Caiazza, Rancho Santa Fe, CA (US);

Jun Urano, Irvine, CA (US);

Maung N. Win, San Diego, CA (US);

Kent S. Boles, La Jolla, CA (US);

Assignee:

Conagen Inc., Bedford, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/68 (2006.01); C12N 15/82 (2006.01); C07K 16/28 (2006.01); C07K 16/00 (2006.01); C07K 16/24 (2006.01); C12N 15/80 (2006.01); C07K 14/405 (2006.01); C07K 16/30 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8258 (2013.01); C07K 14/405 (2013.01); C07K 16/00 (2013.01); C07K 16/24 (2013.01); C07K 16/241 (2013.01); C07K 16/248 (2013.01); C07K 16/249 (2013.01); C07K 16/2803 (2013.01); C07K 16/2809 (2013.01); C07K 16/2839 (2013.01); C07K 16/2866 (2013.01); C07K 16/2875 (2013.01); C07K 16/2878 (2013.01); C07K 16/2896 (2013.01); C07K 16/3069 (2013.01); C07K 16/32 (2013.01); C12N 15/80 (2013.01); C07K 2317/14 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/622 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2319/036 (2013.01);
Abstract

The present invention provides recombinant host cells that produce proteins or therapeutic proteins, and nucleic acid constructs for producing the cells. The cells have nucleic acid constructs that encode a heterologous protein, for example an antibody. The nucleic acid constructs also can have a functional signal sequence that directs the secretion of the protein from the cell. The signal sequence can be any functional signal sequence, and various signal sequences are disclosed herein. The invention also provides methods of producing the proteins.


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