The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2020
Filed:
Jul. 15, 2016
Applicant:
Cornell University, Ithaca, NY (US);
Inventors:
Samie R. Jaffrey, New York, NY (US);
Kate D. Meyer, Durham, NC (US);
Assignee:
Cornell University, Ithaca, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/67 (2006.01); C12P 19/34 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/67 (2013.01); C12P 19/34 (2013.01); C12P 21/02 (2013.01); C12N 2310/333 (2013.01); C12N 2740/16043 (2013.01);
Abstract
The present invention relates to methods and a kit for enhancing the translation ability of an RNA molecule. The methods involve the use of an RNA molecule comprising a methylated adenosine residue in a 5' untranslated region (UTR). Also disclosed are methods for eIF4E-independent translation of an RNA molecule and treatment methods.