The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 10, 2020
Filed:
Dec. 19, 2018
The University of British Columbia, Vancouver, BC, CA;
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Jayachandran Kizhakkedathu, New Westminster, CA;
James H. Morrissey, Champaign, IL (US);
Richard J. Travers, Champaign, IL (US);
Rajesh Shenoi, Richmond, CA;
Manu Thomas Kalathottukaren, Vancouver, CA;
The University of British Columbia, Vancouver, CA;
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Abstract
Provided herein are polymers and methods for their use in binding a phosphate containing biological macromolecules. Specifically, the methods and uses provided herein may be used to inhibit thrombin binding to polyphosphate or as an antithrombotic agent for the treatment of stroke, acute coronary syndrome, pulmonary embolism, atrial fibrillation, venous and arterial thromboembolism, disseminated intravascular coagulation (DIC), deepvein thrombosis (DVT), peripheral artery disease, trauma-induced coagulopathy, extracorporeal circulation, cancer-associated thrombosis, sepsis, septic shock, Systemic Inflammatory Response Syndrome (SIRS), or inflammation.