The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Aug. 13, 2018
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Adimab, Llc, Lebanon, NH (US);

Inventors:

Zhu Chen, Warren, NJ (US);

Kenneth P. Ellsworth, Cranbury, NJ (US);

James A. Milligan, New Egypt, NJ (US);

Elizabeth Oldham, Palo Alto, CA (US);

Dietmar Seiffert, Lawrenceville, NJ (US);

Vaishnavi Ganti, Palo Alto, CA (US);

Mohammad Tabrizifard, Palo Alto, CA (US);

Bianka Prinz, Lebanon, NH (US);

Assignees:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Adimab, LLC, Lebanon, NH (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/36 (2006.01); A61K 39/395 (2006.01); A61P 7/02 (2006.01); C07K 16/30 (2006.01); C07K 14/745 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/36 (2013.01); A61K 39/3955 (2013.01); A61P 7/02 (2018.01); C07K 16/30 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 14/745 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/52 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/71 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

Antibodies that bind the apple 2 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa are described.


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