The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 10, 2020

Filed:

Mar. 10, 2017
Applicants:

The Regents of the University of California, Oakland, CA (US);

Board of Trustees of Michigan State University, East Lansing, MI (US);

Inventors:

Michael C. Pirrung, Riverside, CA (US);

Nicole A. Bakas, Victorville, CA (US);

Andre Bachmann, Grand Rapids, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 281/00 (2006.01); C07D 285/00 (2006.01); C07D 417/12 (2006.01); A61K 45/06 (2006.01); C07K 5/062 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01); A61K 31/395 (2006.01); A61K 31/497 (2006.01);
U.S. Cl.
CPC ...
C07D 281/00 (2013.01); A61K 9/0019 (2013.01); A61K 31/395 (2013.01); A61K 31/497 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 285/00 (2013.01); C07D 417/12 (2013.01); C07K 5/06052 (2013.01);
Abstract

The disclosure provides for compounds having immunoproteasome inhibitory activity, and pharmaceutical compositions made thereof. The disclosure further provides for the use of the compounds and compositions in treating various diseases and disorders in a subject that are associated with immunoproteasome activity, including inflammatory disorders, autoimmune disorders, hematological disorders, and neurodegenerative disorders.


Find Patent Forward Citations

Loading…